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February - 2019

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Showing Journal 6 of 6


Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock

Hernandez G, Ospina-Tascon G, Damiani L, et al for the ANDROMEDA-SHOCK Investigators and the Latin America Intensive Care Network (LIVEN) JAMA, 2019, online Feb 2019

Comment

Should we use repeat lactate measurement to guide resuscitation in septic shock? Are there other measures of perfusion, such as capillary refill time (CRT) that may guide resuscitation and improve outcome?

This RCT was;

  • 424 patients, conducted in Argentina, Chile,...

February



Previous Comments

This study highlights the importance of using bedside clinical parameter such as CRT rather than relatively expensive repetitive biochemical testing in resources saving era , by providing support by the conclusion that CRT-guided resuscitation is not inferior to lactate-guided resuscitation.
FREOKUMAR-06 Dec, 2019 05:35:17 PM