Journal Club - Recent Additions

October - 2019

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Showing Journal 4 of 14

Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock -The SEPSIS-ACT Randomized Clinical Trial

Pierre-Francois Laterre, Scott M. Berry, Allan Blemings, et al for the SEPSIS-ACT Investigators JAMA, 2019, 322(15):1476-1485


The rationale for this trial is that norepinephrine is not always effective at restoring blood pressure in septic shock, and has potential side-effects including myocardial and peripheral ischemia. As a result of this there has been a search for other...


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