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October - 2019

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Reappraisal of Ventilator-Free Days in Critical Care Research

N Yehya, M.O Harhay, M.A.Q Curley, D.A Schoenfield, R.W Reeder Am J Resp Crit Care Med, 2019, 200(7);828-836


The failure-free day concept was developed to summarize the effect of an intervention on morbidity in the presence of the competing event of death. VFDs are typically defined as follows:

  • VFDs = 0 if subject dies within 28 days of mechanical ventilation.
  • VFDs = 28 2 x if...


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