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January - 2020

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Effect of Stress Ulcer Prophylaxis With Proton Pump Inhibitors vs Histamine-2 Receptor Blockers on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation

The PEPTIC Investigators for the Australian and New Zealand Intensive Care Society Clinical Trials Group, Alberta Health Services Critical Care Strategic Clinical Network, and the Irish Critical Care Trials Group JAMA, 2020, Online first 17th Jan


We have been asking questions about stress ulcer prophylaxis for a long time - Should SUP be routine in ventilated ICU patients? What agent should be used? Does the decreasing incidence of symptomatic stress ulcer warrant the possible side effects of routine SUP?



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