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November - 2020

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Remdesivir for the Treatment of Covid-19 — Final Report

J Beigel, K Tomashek, L Dodd, A Mehta, for the ACTT-1 Study Group Members New Eng J Med, 2020, 383:1813-26


The RNA polymerase inhibitor remdesivir has shown nanomolar in-vitro activity against SARS-CoV-2 in human airway epithelial cells and clinical and virologic efficacy in a primate model of SARS-CoV-2. It has safety data in humans infected with Ebola virus. 

This paper reports...


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