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January - 2008

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Intensive Insulin Therapy and Pentastarch Resuscitation in Severe Sepsis

F Brunkhorst, C engel. F Bloos, et al for the German Competence Network Sepsis (SepNet) NEJM, 2008, 358:125-139


In 2008 the international review board stopped the  German SepNet groups IIT in severe sepsis trial after 537 patients were enrolled because of a high incidence of hypoglycaemia in the IIT group (17.6% vs 4.5%). At the time of stopping there was no difference in mortality or...


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