September - 2010
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A Randomized Clinical Trial of Hydroxymethylglutaryl-CoA reductase Inhibition for Acute Lung Injury (The HARP study)Thelma R Craig, Martin J Duffy, Murali Shyamsundar, Cliona McDowell, Cecilia O' Kane, J. Stuart Elborn, and Daniel F McAuley American Journal of Respiratory and Critical Care Medicine, , doi:10.1164/rccm.201003-0423OC This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
September |
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This interesting trial will be seen by statin-enthusiasts as further supportive evidence for their use in inflammatory conditions such as ARDS and sepsis. 80 mechanically ventilated ARDS patients were randomised to either simvastatin or placebo, and while the trial did not show a...