Journal Club - Recent Additions

March - 2012

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A Randomized Trial of Tenecteplase versus Alteplase for Acute Ischemic Stroke

Mark Parsons, Neil Spratt, Andrew Bivard, et al. N Engl J Med, 2012, 366:1099-107.


 This Australian study reports improved reperfusion in ischaemic stroke selected by CT perfusion imaging, using tenecteplase vs alteplase. With prior studies supporting the use of tenecteplase to decrease stroke size, but increased risk of haemorrhage at higher dose, this study...


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