March - 2012
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A Randomized Trial of Tenecteplase versus Alteplase for Acute Ischemic StrokeMark Parsons, Neil Spratt, Andrew Bivard, et al. N Engl J Med, 2012, 366:1099-107. This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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This Australian study reports improved reperfusion in ischaemic stroke selected by CT perfusion imaging, using tenecteplase vs alteplase. With prior studies supporting the use of tenecteplase to decrease stroke size, but increased risk of haemorrhage at higher dose, this study...