Journal Club - Recent Additions

September - 2012

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Showing Journal 5 of 14

Probiotics in the critically ill: A systematic review of the randomized trial evidence

Elaine O. Petrof, Rupinder Dhaliwal, William Manzanares, Jennie Johnstone, Deborah Cook, Daren K. Heyland Crit Care Med, 2012, ahead of print, 11 September doi: 10.1097/CCM.0b01

Comment

The human GIT's normal diverse array of bacterial flora is affected by critical illness, and there has been much interest in the idea of introducing live bacteria for beneficial effect. This systematic review of RCTs that examine the effect of probiotics vs placebo on infectious...

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September

Paper

Readers Comments - 1

Previous Comments

The authors say it all - "the presence of significant clinical and statistical heterogeneity and the lack of statistical precision in some analyses" mean the results are purely hypothesis generating. We need an RCT to sort this out. Yakult anyone?
Jason McCaine-07 Oct, 2012 11:22:09 AM