Journal Club - Recent Additions

March - 2013


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Recombinant Human Activated Protein C for Adults with Septic Shock: a Randomized Controlled Trial

The APROCCHSS Trial Investigators Am J Resp Crit Care Med, 2013, published ahead of print 22nd March


This APC study offers some unique aspects to this highly controversial area of intensive care research. For a start it is the only investigator led RCT of APC (PROWESS, PROWESS-SHOCK, etc all commercial trials). It was conducted in 24 ICU's in France, experienced in the use of APC, with a 2x2...


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