March - 2013
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Reduced Cortisol Metabolism during Critical IllnessEva Boonen, Hilke Vervenne, Philippe Meersseman et al N Engl J Med, 2013, Online first March 19, DOI: 10.1056/NEJMoa1214969 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
March |
Previous Comments
| Its well worth listening to the podcast with Jeremy Cohen on this topic - the cascade is so ridiculously complicated that linking total serum cortisol to outcome was never going to work. You sum it up in the last sentence Neil - we have no idea what we're doing! | |
| Todd Fraser-20 Mar, 2013 08:38:03 PM | |
Comment
This observational study from Van den Berghe and colleagues in Leuven looks at cortisol metabolism in critically ill patients compared to matched controls. They report the ICU patients have an increase total and free circulating cortisol, lower corticotropin, increased cortisol...