August - 2013
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Effects of dobutamine on systemic, regional and microcirculatory perfusion parameters in septic shock: a randomized, placebo-controlled, double-blind, crossover studyGlenn Hernandez, Alejandro Bruhn, Cecilia Luengo, et al Int Car Med, 2013, 39(8);1435-1443 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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This small surrogate outcome RCT is of interest because it looks at dobutamine in septic shock, one of the components of the Rivers (and subsequent EGDT trials) study that seemed controversial. In summary dobutamine failed to improve sublingual microcirculatory, metabolic,...