Journal Club - Recent Additions

September - 2013

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Showing Journal 4 of 12


Prevalence and prognosis of cor pulmonale during protective ventilation for acute respiratory distress syndrome

Florence Boissier, Sandrine Katsahian, Keyvan Razazi, et al Int Care Med, 2013, 39:1725–1733

Comment

ARDS is associated with pulmonary vascular dysfunction, increased RV work, with the potential for progressive RV dysfunction. This prospective observational study describes the incidence of core pulmonale in patients receiving a protective ventilation strategy for ARDS. 

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September



Previous Comments

corpulmonale & Rv dysfunction will also be detrimental for use of high peep in ARDS patients apart from the mortality as mentioned by this study So essentially all the patients with ARDS should be screened for the same
Kedar Toraskar-30 Sep, 2013 01:36:09 AM

At one point in their manuscript they mention that they did not require patient consent as TOE is done routinely to "guide" their hemodynamic management. Then later they say that no respiratory and hemodynamic management was done based on TOE findings. Significant possibility of bias in this study. Also MAP was significantly lower in the cor pulmonale group. We all know the importance of MAP for RCPP and RV function. - shivesh
shiv-02 Oct, 2013 07:21:14 AM