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September - 2014

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Effect of Fenoldopam on Use of Renal Replacement Therapy Among Patients With Acute Kidney Injury After Cardiac Surgery A Randomized Clinical Trial

Tiziana Bove, Alberto Zangrillo, Fabio Guarracino, et al JAMA, 2014, online 29th sept

Comment

The rationale for this study is that AKI requiring RRT after cardiac surgery occurs in 5% of patients with an associated mortality up to 60%. Fenoldopam, a selective D1 agonist, induces vasodilation of the renal, mesenteric, peripheral, and coronary arteries, without D2 effects,...


September



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