A Clinical Trial of Progesterone for Severe Traumatic Brain Injury
B Skolnick, A Maas, R Narayan, et al for the SYNAPSE Trial InvestigatorsNEJM, 2014, online 1st Dec 2014
Comment
This 1 of 2 trials in the NEJM investigating the role of progesterone e in TBI.
Progesterone is a potent neurosteroid, and preclinical studies show early administration after experimental TBI in lab animals reduces cerebral edema, neuronal...
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