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Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest

J Dankiewicz, T Cronberg, G Lilja, etal for the TTM2 Trial Investigators New Eng J Med, 2021, 384:2283-2294


Guidelines strongly recommend targeted temperature management with a constant target between 32C and 36C. However they also state low certainty. The evidence supports this;

  • 2019 HYPERION (NEJM): 584 pts moderate TTM (33C for 24hrs, rewarm 0.25-0.5 C/hr to 36.5-37.5C, then...


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