Journal Club - Recent Additions

October - 2021


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Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial

M LeMAy, C Osborne, J Russo et al JAMA, 2021, 326(15):1494-1503


This RCT, the CAPITAL CHILL trial  compares moderate (31C) to mild (34C) hypothermia in comatose adult patients following OHCA. 

Why? An impressive body of evidence has emerged over the last two decades, with varied temperatures (from 32-34 to normothermia), duration...


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