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May - 2022

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Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children- A randomised clinical trial

P Ramnarayan, A Richard-Belle, L Drikite et al for the FIRST-ABC Step-Down RCT Investigators and the Paediatric Critical Care Society Study Group. JAMA, 2022, 327(16):1555-1565


This trial set out to answer the question - In critically ill children clinically assessed to require noninvasive respiratory support following extubation, is the first-line use of high-flow nasal cannula (HFNC) therapy non-inferior to continuous positive airway pressure (CPAP) in terms...


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