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June - 2022

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Showing Journal 4 of 6


Restriction of Intravenous Fluid in ICU Patients with Septic Shock

T.S.Meyhoff, P.B.Hjortrup, J.Wettersley, et al for the CLASSIC Trial Group NEJM, 2022, online 1st

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The Surviving Sepsis Campaign suggests 30 ml/kg IV fluid as initial therapy in septic shock to restore circulation. Whether more or less fluid is better is no clear. The CLASSIC trial set out to evaluate the effects of restriction of IV fluid on mortality in adult patients with septic shock in...


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