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February - 2023

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Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension

The National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network New Eng J Med, 2023, Online Jan


The optimal fluid therapy in sepsis - a balance of increasing absolute or vasodilation related functionally reduced intravascular volume, stroke volume and cardiac output, improving micro vascular perfusion 


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