05:05 PM May 12th
JAMA MIS-C - Observational study of combined treatment with IVIG + methylprednisolone vs IVIG alone associated with reduced treatment failure, new LV dysfunction, hemodynamic support, and PICU LOS better course of fever in children with MIS-C.
02:05 PM May 11th
JAMA REALITY - Restrictive transfusion strategy compared with a liberal strategy resulted in a noninferior rate of major cardiovascular events among patients with acute myocardial infarction and anemia.
07:05 PM May 10th
NEJM CONFIRM terlipressin with albumin more effective than albumin alone at reversing hepatorenal syndrome in adults with cirrhosis and HRS-1. Interesting cautionary discussion about terlipressin association with more serious adverse events, particularly respiratory failure..
04:05 PM May 10th
NEJM COVACTA adults hospitalised with COVID-19 pneumonia, use of tocilizumab was not assicated with difference in clinical status at day 28, or secondary outcomes. Signal of difference in hospital LOS, ICU LOS, ventilator free days favoured tocilizumab.
03:05 PM May 10th
REMAP-CAP IMT IL-6 domain report improved cardiovascular and respiratory organ support free days, and overall survival, associated with the administration of tocilizumab or sarilumab in critically ill adult patients with COVID-19