Recent News

  • 10:11 AM Nov 11th
    NEJM AID-ICU regular haloperidol vs placebo + PRN haloperidol did not result in difference in dose review (median cumulative 32.5mg both groups) of hospital free days or outcomes in adult patients in ICU with delirium
  • 10:11 AM Nov 11th
    NEJM PILOT Trial: Lower, medium, or higher oxygen target not associated difference in outcomes in adult patients requiring mechanical ventilation. This suggests limiting exposure to supplemental oxygen by targeting different SpO2 ranges does not prevent death or liberation from mechanical ventilation, and there is no U shaped curve in this range.
  • 11:11 AM Nov 9th
    JAMA ECMO associated high rate new mental health diagnosis following hospital discharge. Depression, anxiety, PTSD most common. Identifies vulnerable patients, need for long-term outcome research aimed at better survivorship
  • 10:11 AM Nov 9th
    JAMA EXACT Trial: Pre-hospital oxygen target SpO2 90-94% vs 98-100% in ventilated OHCA associated survival to hospital discharge 38% vs 48% (diff -9.6%, 95% CI -18.9 to -0.2%, OR 0.68, 95% CI 0.46-1.00, p=0.05). Hypoxia twice (31 vs16%), no diff other outcomes. Trial stopped early for COVID. Does not support use of lower SpO2 targets in this population.
  • 04:11 PM Nov 6th
    NEJM What COVID has taught the world about ethics - A philosophical and operational framework for how to bridge the gap between public insistence on "fairness", "equity", "solidarity" and policy that does not deliver on these values. 

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