07:05 AM May 11th
RELIEF Trial: Restrictive vs liberal fluid in patients with major abdominal surgery, no diff 1-year disability-free survival (81.9% R vs 82.3% L, HR, 1.05; 95% CI, 0.9 to 1.2; P=0.6). Restrictive higher rate acute kidney injury, no difference ICU LOS or MV.
05:05 PM May 5th
JC: Tenecteplase superior to alteplase pre-thrombectomy in ischaemic large vessel stroke for reperfusion and average 90-d functional outcome. Return to independent living not significantly different (64% T vs 51% A, p=0.06)
09:05 AM May 5th
JC: Nocturnal low-dose dexmedetomidine in critically ill adults associated reduced delirium, days spent with coma, and opiate requirements.
10:05 AM May 4th
JC: Radial vs SVG associated lower rate of AMI and re-vascularisation, graft occlusion at 5-years. No difference survival. Sub-group analysis suggests certain populations benefit more.
08:05 AM May 4th
JC: Ticagrelor associated better 1-yr SVC patency after CABG in elective, low-risk patients. Next steps - better functional or clinical outcomes? Will bleeding risk emerge?
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